During the past two and one half years, from March, 1969, to September, 1971 we have encountered 11 cases of Wilkie’s syndrome which were treated and diagnostically certified by operation at Presbyterian Medical Center in Jeon-Ju.
An analysis of our data reveals the following:
1) Among the 5,750 upper gastrointestinal studies during the above-mentioned period 11 cases were found, a percentage of about 0.2%.
2) The peak age incidence was 21~30 years and range was from 17 years to 49 years.
3) The sex distribution was more in male than female, and the ratio was 7 to 4.
4) the predominant symptoms were epigastric pain (100%), indigestion (72.7%), epigastric fullness (54.5%) and vomiting (45.4%). Weight loss was the most important physical finding, occurring in 90.9% of our patients. The next most frequent sign was epigastric tenderness (63.6%).
5) The following concomitant diseases were diagnosed: Visceroptosis: 3 cases (27.3%), Duodenal ulcer: 2 cases(18.2%); Cholecystitis 1 case with duodenal ulcer, Pancreatitis 1 case; Hyperthyroidism 1 case; Salmonellosis 1 case; and Pyloric stenosis 1 case.
6) The average duration of preoperative symptoms and signs was about 5 years and the range was from 4 months to 15 years.
7) As to treatment, duodenojejunostomy was the principle in all cases. Even when a duodenal ulcer was present concomitantly, we added duodenojejunostomy simultaneously. No operative mortality or complication occurred.
8) The average weight loss was 10.5kg, or about 17% of body weight. The most significant loss was recorded 17 kg, or. 32.7% of body weight.
9) Satisfactorily follow-up study was almost completely done. Six patients are symptom-free and two patients state that marked improvement occurred. The average weight gain was 5.7 kg (13.4%). and the best increase was 10 kg.
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